Table 1.
Baseline characteristics of the 3,5,3′-triiodothyronine challenge study
| Offspring (n = 14) | Partners (n = 13) | P | |
|---|---|---|---|
| Age of mother, ya | 94 (91-97) | 75 (70-87) | .003 |
| Age of father, ya | 94 (73-96) | 78 (68-84) | .06 |
| Men, n (%) | 9 (64) | 5 (36) | .18 |
| Age, y | 69 (67-72) | 70 (66-72) | .63 |
| BMI, kg/m2 | 25.5 (3.8) | 26.2 (4.3) | .61 |
| Weight, kg | 79.0 (14.3) | 78.3 (14.1) | .96 |
| Height, cm | 175.6 (10.2) | 172.5 (9.0) | .54 |
| Fat mass, kg | 22.7 (6.3) | 26.0 (9.8) | .31 |
| Lean mass, kga | 59.7 (42.1-64.8) | 52.3 (43.9-65.1) | .58 |
| GFR, mL/min/1.73 m2,b | 75.2 (13.5) | 77.8 (8.2) | .56 |
| AST, U/La | 21.7 (19.8-24.0) | 23.0 (20.0-26.8) | .34 |
| ALT, U/L | 19.9 (5.8) | 20.5 (5.0) | .80 |
| TSH, mU/L | 2.6 (1.2) | 2.0 (1.1) | .05 |
| fT4, pmol/L | 14.3 (2.1) | 15.1 (1.9) | .26 |
| fT3, pmol/L | 4.39 (0.36) | 4.02 (0.49) | .03 |
| fT3/fT4 ratio | 0.313 (0.046) | 0.267 (0.029) | .005 |
Data are shown as mean (SD) or as median and interquartile range.
Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; BMI, body mass index; fT4, free thyroxine; GFR, glomerular filtration rate; TSH, thyrotropin.
aMedian (interquartile range).
bIn offspring, based on 13 values because of 1 missing sample.