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. Author manuscript; available in PMC: 2020 Nov 12.
Published in final edited form as: N Engl J Med. 2020 Nov 12;383(20):1932–1940. doi: 10.1056/NEJMoa2002276

Table 2.

Matched odds of intussusception in the risk window after first, second and third dose of rotavirus vaccination in age-, gender- and location matched case-control pairs (n=162) of Indian infants with a confirmed rotavirus vaccination history with the vaccine under study

Doses of rotavirus vaccine Risk window relative to reference date# No. of cases in risk window No. of controls in risk window Matched odds ratio
Dose 1 1-7 days 1 1 1 (0.12, 78.49)
8-21 days 1 5 0 (0, 1.51)
1-21 days 2 6 0 (0, 1.51)
Dose 2 1-7 days 1 1 1 (0.01, 78.49)
8-21 days 3 3 1 (0.07, 13.79)
1-21 days 4 4 1 (0.13, 7.46)
Dose 3 1-7 days 6 3 2.5 (0.41, 26.25)
8-21 days 7 7 1 (0.26, 3.74)
1-21 days 13 10 1.4 (0.49, 4.42)
#

The date of intussusception onset was defined as date of onset of symptoms