Table 2.
Matched odds of intussusception in the risk window after first, second and third dose of rotavirus vaccination in age-, gender- and location matched case-control pairs (n=162) of Indian infants with a confirmed rotavirus vaccination history with the vaccine under study
Doses of rotavirus vaccine | Risk window relative to reference date# | No. of cases in risk window | No. of controls in risk window | Matched odds ratio |
---|---|---|---|---|
Dose 1 | 1-7 days | 1 | 1 | 1 (0.12, 78.49) |
8-21 days | 1 | 5 | 0 (0, 1.51) | |
1-21 days | 2 | 6 | 0 (0, 1.51) | |
Dose 2 | 1-7 days | 1 | 1 | 1 (0.01, 78.49) |
8-21 days | 3 | 3 | 1 (0.07, 13.79) | |
1-21 days | 4 | 4 | 1 (0.13, 7.46) | |
Dose 3 | 1-7 days | 6 | 3 | 2.5 (0.41, 26.25) |
8-21 days | 7 | 7 | 1 (0.26, 3.74) | |
1-21 days | 13 | 10 | 1.4 (0.49, 4.42) |
The date of intussusception onset was defined as date of onset of symptoms