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. 2020 Sep 1;9:e58675. doi: 10.7554/eLife.58675

Table 1. Binding affinities of PHF1/MTF2 mutants with the H3tK27me3 peptide.

PHF1 ITC (µM)
W41A NB
Y47A NB
F65A NB
F71A 192 ± 18
L38A 125 ± 9
L45A 178 ± 9
L46A 127 ± 8
L46Y 50 ± 5
L48A 81 ± 2
L38A, L45A, L46A, L48A >500
E66A >200
MTF2 ITC (µM)
S86F 91 ± 21
S86Y 110 ± 11

NB indicates no detectable binding.