Table 4.
Multivariate Cox regression analysis.
| Covariate | HR (95% CI) | p Value |
|---|---|---|
| All patients | ||
| Any NTP in C1–2 | ||
| No | ||
| Yes | 0.49 (0.34–0.70) | <0.001 |
| ECOG PS | ||
| 0 | ||
| 1 | 1.51 (1.12–2.04) | 0.007 |
| # Prior lines of therapy | ||
| 1–2 | ||
| 3+ | 1.39 (1.02–1.87) | 0.033 |
| Breast patients | ||
| Any NTP in C1–2 | ||
| No | ||
| Yes | 0.19 (0.07–0.52) | 0.001 |
| Age | ||
| <Median | ||
| ≥Median | 0.50 (0.29–0.89) | 0.017 |
| Immediate prior line chemo | ||
| No | ||
| Yes | 1.76 (1.02–3.03) | 0.042 |
| Non-breast patients | ||
| Any NTP in C1–2 | ||
| No | ||
| Yes | 0.56 (0.37–0.83) | 0.004 |
| ECOG PS | ||
| 0 | ||
| 1 | 1.68 (1.15–2.43) | 0.006 |
| # Prior lines of therapy | ||
| 1–2 | ||
| 3+ | 1.81 (1.22–2.70) | 0.003 |