Table 3.
The value of independent variables in different Cox proportional hazards models as predictors of disease-free survival in high-risk II colon cancer.
| Independent variables in different Cox proportional hazards models | HR (95% CI) | P-value |
|---|---|---|
| Stromaa | 0.186 | |
| Low stroma | 1 | |
| High stroma | 1.657 (0.784–3.520) | |
| DNA ploidya | 0.015 | |
| Diploid | 1 | |
| Non-diploid | 2.585 (1.206–5.540) | |
| Nucleotypinga | 0.001 | |
| Chromatin homogeneous | 1 | |
| Chromatin heterogeneous | 3.309 (1.668–6.564) | |
| DNA ploidy and nucleotypinga | 0.001 | |
| Diploid and chromatin homogeneous | 1 | |
| Diploid and chromatin heterogeneous or non-diploid and chromatin homogeneous | 1.647 (0.700–4.002) | |
| Non-diploid and chromatin heterogeneous | 4.439 (1.909–10.319) | |
| Stroma and nucleotypinga | 0.008 | |
| Chromatin homogeneous and low stroma | 1 | |
| Chromatin homogeneous and high stroma or chromatin heterogeneous and low stroma | 2.002 (0.952–4.211) | |
| Chromatin heterogeneous and high stroma | 4.319 (1.655–11.268) | |
| Stroma and DNA ploidya | 0.024 | |
| Diploid and low stroma | 1 | |
| Diploid and high stroma or non-diploid and low stroma | 1.818 (0.786–4.205) | |
| Non-diploid and high stroma | 3.764 (1.442–9.852) |
A two-sided p-value of less than 0.008 was considered statistically significant.
aAdjusted age and pathological T-stage.