Table 1.
Details of Δ0, i.e. relative changes of T1, T1ρ, T2, and T2* at δ0 during the pre- and post-exposure measurement series, as a function of trypsin exposure and region-of-interest.
| Δ0 | p value | |
|---|---|---|
| T1 | ||
| Low trypsin | ||
| Entire | 0.4 ± 2.9 | 0.846 |
| SPA | − 0.4 ± 3.2 | 0.625 |
| SPA upper | − 0.1 ± 1.8 | 0.922 |
| SPA lower | − 0.7 ± 6.5 | 0.625 |
| PPA | 1.4 ± 2.8 | 0.232 |
| PPA upper | 2.1 ± 2.3 | 0.027 |
| PPA lower | 0.7 ± 5.0 | 0.695 |
| High trypsin | ||
| Entire | 1.9 ± 3.5 | 0.131 |
| SPA | 1.9 ± 3.8 | 0.131 |
| SPA upper | 4.0 ± 3.3 | 0.004 |
| SPA lower | − 0.4 ± 6.1 | 0.846 |
| PPA | 2.1 ± 3.5 | 0.193 |
| PPA upper | 4.6 ± 3.2 | 0.004 |
| PPA lower | − 2.6 ± 5.2 | 0.275 |
| Controls | ||
| Entire | − 1.3 ± 1.3 | 0.027 |
| SPA | − 0.9 ± 1.6 | 0.084 |
| SPA upper | − 1.2 ± 2.0 | 0.105 |
| SPA lower | − 1.1 ± 2.5 | 0.275 |
| PPA | − 1.3 ± 2.2 | 0.131 |
| PPA upper | − 0.8 ± 2.3 | 0.275 |
| PPA lower | − 1.4 ± 3.7 | 0.275 |
| T1ρ | ||
| Low trypsin | ||
| Entire | 0.6 ± 7.9 | 0.922 |
| SPA | 0.4 ± 7.5 | 0.999 |
| SPA upper | 0.6 ± 8.6 | 0.999 |
| SPA lower | 0.2 ± 8.4 | 0.770 |
| PPA | − 0.7 ± 9.7 | 0.999 |
| PPA upper | 0.5 ± 11.4 | 0.922 |
| PPA lower | − 1.6 ± 9.9 | 0.999 |
| High trypsin | ||
| Entire | 3.3 ± 11.9 | 0.492 |
| SPA | 4.2 ± 13.4 | 0.322 |
| SPA upper | 5.6 ± 15.5 | 0.322 |
| SPA lower | 2.9 ± 12.6 | 0.557 |
| PPA | 1.4 ± 12.6 | 0.846 |
| PPA upper | 4.1 ± 12.3 | 0.557 |
| PPA lower | − 1.8 ± 14.5 | 0.770 |
| Controls | ||
| Entire | − 12.1 ± 8.1 | 0.002 |
| SPA | − 12.2 ± 7.7 | 0.002 |
| SPA upper | − 11.8 ± 9.2 | 0.002 |
| SPA lower | − 12.7 ± 9.4 | 0.004 |
| PPA | − 12.3 ± 9.3 | 0.004 |
| PPA upper | − 12.1 ± 8.8 | 0.004 |
| PPA lower | − 12.8 ± 11.2 | 0.004 |
| T2 | ||
| Low trypsin | ||
| Entire | 4.5 ± 9.7 | 0.232 |
| SPA | 4.3 ± 10.2 | 0.275 |
| SPA upper | 5.6 ± 11.1 | 0.193 |
| SPA lower | 2.5 ± 10.5 | 0.846 |
| PPA | 4.7 ± 9.5 | 0.105 |
| PPA upper | 6.0 ± 11.4 | 0.105 |
| PPA lower | 4.1 ± 10.6 | 0.432 |
| High trypsin | ||
| Entire | 9.5 ± 10.7 | 0.020 |
| SPA | 10.1 ± 10.2 | 0.014 |
| SPA upper | 10.9 ± 11.1 | 0.014 |
| SPA lower | 8.7 ± 12.1 | 0.049 |
| PPA | 9.5 ± 13.4 | 0.064 |
| PPA upper | 10.6 ± 13.4 | 0.049 |
| PPA lower | 8.5 ± 15.9 | 0.193 |
| Controls | ||
| Entire | − 12.4 ± 8.3 | 0.002 |
| SPA | − 12.5 ± 9.1 | 0.002 |
| SPA upper | − 11.2 ± 6.0 | 0.002 |
| SPA lower | − 14.6 ± 13.6 | 0.004 |
| PPA | − 12.1 ± 6.3 | 0.004 |
| PPA upper | − 9.9 ± 5.6 | 0.004 |
| PPA lower | − 16.4 ± 9.7 | 0.004 |
| T2* | ||
| Low trypsin | ||
| Entire | 5.8 ± 8.9 | 0.105 |
| SPA | 5.8 ± 8.8 | 0.105 |
| SPA upper | 6.5 ± 10.1 | 0.105 |
| SPA lower | 4.7 ± 12.2 | 0.375 |
| PPA | 5.3 ± 9.3 | 0.131 |
| PPA upper | 6.3 ± 10.9 | 0.160 |
| PPA lower | 4.9 ± 12.7 | 0.557 |
| High trypsin | ||
| Entire | 7.4 ± 8.5 | 0.014 |
| SPA | 8.5 ± 8.6 | 0.010 |
| SPA upper | 9.7 ± 9.3 | 0.020 |
| SPA lower | 8.5 ± 10.6 | 0.027 |
| PPA | 7.3 ± 12.9 | 0.275 |
| PPA upper | 7.5 ± 12.0 | 0.160 |
| PPA lower | 8.4 ± 19.6 | 0.432 |
| Controls | ||
| Entire | − 8.3 ± 9.1 | 0.014 |
| SPA | − 8.5 ± 10.7 | 0.037 |
| SPA upper | − 7.8 ± 7.5 | 0.010 |
| SPA lower | − 9.8 ± 16.1 | 0.105 |
| PPA | − 6.5 ± 9.4 | 0.049 |
| PPA upper | − 6.3 ± 9.2 | 0.049 |
| PPA lower | − 8.2 ± 15.6 | 0.049 |
Δ0 was calculated as Δ0 = ((δ0post/δ0pre) − 1) * 100 [%], where δ0post and δ0pre are the respective post- and pre-exposure absolute parameter values at δ0. Data are mean ± standard deviation [%]. Wilcoxon matched pairs test was used to assess differences between δ0pre and δ0post. Significant differences are indicated in bold type.