Table 2.

Adjusted differences in PGT vs no PGT for all cycles (N = 28,214)

Outcome	PGT (N = 3712)	No PGT (N = 24,502)	Estimate without interaction (95% CI)	p value	Fresh PGT (N = 2050)	Fresh no PGT (N = 14,976)	Frozen PGT (N = 1662)	Frozen no PGT (N = 9526)	Effect of PGT within fresh cycles (95% CI)	p value	Effect of PGT within frozen cycles (95% CI)	p value	Interaction p value
GBO	622 (16.8)	5448 (22.2)	0.78 (0.73, 0.84)	< 0.001	198 (9.7)	3553 (23.7)	424 (25.5)	1895 (19.9)	0.47 (0.41, 0.54)	< 0.001	1.12 (1.02, 1.22)	0.018	< 0.001
LB	1139 (30.7)	11,200 (45.7)	0.72 (0.69, 0.75)	< 0.001	402 (19.6)	7550 (50.4)	737 (44.3)	3650 (38.3)	0.43 (0.39, 0.47)	< 0.001	1.11 (1.05, 1.17)	< 0.001	< 0.001
Term	753 (20.3)	6819 (27.8)	0.76 (0.71, 0.81)	< 0.001	256 (12.5)	4477 (29.9)	497 (29.9)	2342 (24.6)	0.47 (0.42, 0.53)	< 0.001	1.09 (1.004, 1.18)	0.040	< 0.001
SAB	237 (6.4)	2162 (8.8)	0.74 (0.65, 0.85)	< 0.001	75 (3.7)	1251 (8.4)	162 (9.7)	911 (9.6)	0.48 (0.38, 0.60)	< 0.001	0.99 (0.85, 1.17)	0.960	< 0.001
CP	1384 (37.3)	13,485 (55.0)	0.73 (0.70, 0.76)	< 0.001	478 (23.3)	8882 (59.3)	906 (54.5)	4603 (48.3)	0.44 (0.40, 0.47)	< 0.001	1.10 (1.05, 1.15)	< 0.001	< 0.001
BP	207 (5.6)	2077 (8.5)	0.66 (0.58, 0.77)	< 0.001	50 (2.4)	1053 (7.0)	157 (9.4)	1024 (10.7)	0.38 (0.28, 0.50)	< 0.001	0.87 (0.74, 1.03)	0.108	< 0.001
Singleton	959 (25.8)	8348 (34.1)	0.81 (0.77, 0.85)	< 0.001	307 (15.0)	5335 (35.6)	652 (39.2)	3013 (31.6)	0.50 (0.45, 0.55)	< 0.001	1.11 (1.04, 1.18)	0.002	< 0.001

Table includes adjusted outcomes for all cycles (top) and including the interaction term (bottom). All estimates adjusted for donor age, patient age, BMI, smoking status, parity, history of preterm birth, history of spontaneous birth, assisted hatching, single embryo transfer, cycle type, and blastocyst transfer

GBO, good obstetric outcome; LB, live birth; Term, term pregnancy; SAB, spontaneous abortion; CP, clinical pregnancy; BP, biochemical pregnancy; PGT, preimplantation genetic testing