Table 3.
Adjusted differences in PGT vs no PGT for cycles that resulted in an embryo transfer
| Outcome | PGT (N = 2372) | No PGT (N = 23,013) | Adjusted estimate (95% CI) | p value |
|---|---|---|---|---|
| Good birth outcome | 622 (26.2) | 5448 (23.7) | 1.08 (1.001, 1.16) | 0.047 |
| Live birth | 1139 (48) | 11,200 (48.7) | 1.07 (1.03, 1.12) | 0.002 |
| Term | 753 (31.7) | 6819 (29.6) | 1.07 (1.01, 1.14) | 0.032 |
| Spontaneous abortion | 237 (10) | 2162 (9.4) | 1.05 (0.92, 1.21) | 0.430 |
| Clinical pregnancy | 1384 (58.3) | 13,484 (58.6) | 1.07 (1.03, 1.11) | < 0.001 |
| Biochemical | 207 (8.7) | 2074 (9) | 0.89 (0.77, 1.03) | 0.109 |
| Singleton | 959 (40.4) | 8348 (36.3) | 1.08 (1.03, 1.14) | 0.004 |
| Z-score for GAAWa | 0 (1.1) | − 0.1 (1.1) | − 0.07 (− 0.14, 0.00) | 0.050 |
| OIR* | 0.8 (0.4) | 0.8 (0.3) | 0.00 (− 0.02, 0.02) | 0.654 |
aContinuous outcome
All estimates adjusted for donor age, patient age, BMI, smoking status, parity, history of preterm birth, history of spontaneous birth, assisted hatching, single embryo transfer, cycle type, and blastocyst transfer
PGT, preimplantation genetic testing; GAAW, gestational age-adjusted weight; OIR, ongoing implantation rate