Table 2.
Significant mtDNA D-loop SNPs with a minor allele frequency > 5% in endometriosis and controls
| SNP | Frequency | OR (95% CI) | p value | |
|---|---|---|---|---|
| Endometriosis (n = 125) | Control (n = 124) | |||
| T195C | 6 (4.80%) | 17 (13.71%) | 0.317 (0.121–0.834) | 0.02 |
| AC523–524 del | 58 (46.40%) | 42 (33.87%) | 1.690 (1.013–2.819) | 0.044 |
| T16172C | 21 (16.80%) | 9 (7.26%) | 2.580 (1.131–5.886) | 0.024 |
| A16183C | 24 (19.20%) | 40 (32.26%) | 0.499 (0.279–0.894) | 0.019 |
| T16189C | 32 (25.60%) | 49 (39.52%) | 0.527 (0.307–0.903) | 0.02 |
| 16193C ins | 9 (7.20%) | 25 (20.16%) | 0.307 (0.137–0.689) | 0.004 |
| C16290T | 17 (13.60%) | 6 (4.84%) | 3.096 (1.178–8.139) | 0.022 |
Logistic regression analysis, data are expressed as n (%); SNP: single nucleotide polymorphism; OR: odds ratio; CI: confidence interval