Table 4.
Comparison of obstetric outcomes of live birth from single euploidy or mosaic embryo transfers according to type of mosaicism
| Term development cycles (n) | Karyotyping normal % (n) | Congenital anomalies%* | Gestational weeks at delivery | Birth weight | |
|---|---|---|---|---|---|
| Euploidy | 120 | 100 (121) | 0 (0) | 38.4 ± 1.7 | 3146.2 ± 450.0 |
| Mosaicism | 36 | 100 (40) | 0 (0) | 38.3 ± 1.7 | 2997.7 ± 501.1 |
| Mosaic type: low percentages of mosaicism | |||||
| 30% | 27 | 100 (29) | 0 (0) | 38.4 ± 1.6 | 3019.2 ± 520.3 |
| 40% | 9 | 100 (11) | 0 (0) | 38.2 ± 1.8 | 2927.1 ± 461.0 |
| Mosaic type: mosaicism from different chromosome structures involved | |||||
| Whole | 5 | 100 (5) | 0 (0) | 39.4 ± 1.8 | 3280.0 ± 180.8 |
| Segmental | 25 | 100 (29) | 0 (0) | 37.9 ± 1.7 | 2951.0 ± 541.2 |
| Complex | 6 | 100 (6) | 0 (0) | 39.1 ± 0.9 | 3020.2 ± 462.5 |
| Mosaic type: no. of chromosomes involved | |||||
| 1 | 20 | 100 (24) | 0 (0) | 38.1 ± 1.8 | 2913.6 ± 463.6 |
| 2 | 11 | 100 (11) | 0 (0) | 38.8 ± 1.6 | 3102.3 ± 603.9 |
| >2 | 5 | 100 (5) | 0 (0) | 38.0 ± 1.0 | 3189.0 ± 432.9 |
No significant differences were observed in any factor
*Congenital anomaly was defined as apparent defects in appearance, including nervous system, eye and face, cardiovascular disease, digestive system, urinary and renal system, muscle skeletal system, and chromosomal abnormalities