Table 2.
Determinants of outcome: Overall Survival (OS) and Recurrence Free Survival (RFS) in 52 iSMC cases −Cox regression analyses
| OS | RFS | |||||
|---|---|---|---|---|---|---|
| HR | CI 95% | p | HR | CI 95% | p | |
| Tumor type (pure iSMC vs miSMC) | 2.444 | 0.471-12.675 | 0.287 | 2.158 | 0.663-7.020 | 0.201 |
| Age 50<;>50 years | 1.834 | 0.347-9.702 | 0.476 | 1.379 | 0.160-3.273 | 0.676 |
| FIGO stage (I vs II-IV) | 6.765 | 1.490-30.500 | 0.013 | 3.469 | 1.120-10.746 | 0.031 |
| Surgical treatment (without vs with lymph node dissection) | 57.526 | 0.077-42858,438 | 0.23 | 4.782 | 1.041-21.974 | 0.044 |
| Adjuvant treatment (yes vs no) | 3.382 | 0.378-28.493 | 0.281 | 3.324 | 0.700-15.792 | 0.131 |
| Tumor size (<4cm vs >=4cm) | 32.114 | 3.583-287.821 | 0.02 | 10.261 | 2.619-41.794 | 0.001 |
| HPV status (HPV testing) (pos vs neg) | 3.69 | 0.055-1.347 | 0.111 | 2.197 | 0.112-1.856 | 0.273 |
| Tumor grade (1,2 vs 3) | 2.032 | 0.244-16.923 | 0.512 | 3.841 | 0.495-29.831 | 0.198 |
| Silva pattern (A, B vs C) | 22.565 | 0.000-8545346.7 | 0.634 | 1.187 | 0.109-6.494 | 0.869 |
| Lympho-vascular invasion (yes vs no) | 3.289 | 0.633-17.093 | 0.157 | 2.998 | 0.893-10.071 | 0.076 |
| Lymph node metastasis (yes vs no) | 14.95 | 1.694-131.912 | 0.015 | 5.52 | 1.569-19.424 | 0.008 |
| Local/pelvic recurrences (yes vs no) | 12.323 | 1.436-105.770 | 0.022 | 18.089 | 2.040-160.361 | 0.009 |