Table 3.

Colonoscopy findings, FIT concentration and AUC according to study definitions.

	n (%)	FIT value μg/g (Q1-Q3)	AUC (95%CI)
Any lesion*	261 (35.9)	18.9 (0.0–219.4)	0.703 (0.661–0.745)
Clinically significant pathology+	142 (19.5)	84.53 (3.8–1097.7)	0.813 (0.768–0.858)
Neoplasia	182 (25.0)	24.95(0.0–322.5)	0.724 (0.678–0.770)
Advanced neoplasia	115 (15.8)	75.55 (2.9–871.8)	0.791 (0.741–0.841)
Cancer	36 (5.0)	1079.05 (83.5–3178.4)	0.903 (0.848–0.957)

^*Any lesion is defined as presence of any finding in the colonoscopy [1 case defined as others (serrated polyp) is included].

⁺Clinically significant pathology is defined as presence of CRC, advanced adenoma, inflammatory bowel disease or vascular pathology [2 cases defined as others (serrated polyp and rectal ulcer) are included].