. Author manuscript; available in PMC: 2021 Jul 1.

Published in final edited form as: J Clin Lipidol. 2020 May 6;14(4):438–447.e3. doi: 10.1016/j.jacl.2020.04.009

Table 2.

Association between TG and CVD events

TG measurement	C- statistic	AUC	p-value	HR (per 1 SD)	SD
Baseline (mg/dL)	0.565	10273.0	0.0007	1.06 (1.02 -1.09)	104.2 mg/dL
Average (mg/dL)	0.603	10208.7	<0.0001	1.02 (1.01 – 1.02)	71.8 mg/dL
Log₂Average (per doubling of TG)	0.603	10207.4	<0.0001	1.40 (1.30 – 1.51)	0.67
Maximum^* (mg/dL)	0.584	10234.1	<0.0001	1.01 (1.00 – 1.01)	136.2 mg/dL

AUC, area under curve, defined as triglycerides x years of exposure using trapezoid rule; COV, coefficient of variation defined as standard deviation/mean; CVD, cardiovascular disease; HR, hazard ratio; SD, standard deviation; TG, triglyceride

Relationship non-linear; modeled using restricted cubic splines using 4 knots.