TABLE 3.
Cut-off at 32 weeks. Crude results. Differences between early onset preeclampsia (EOP) and late onset preeclampsia (LOP): EOP, n = 466 (26.8%); LOP: n = 1270 (73.2%). Multiparae with preeclampsia: EOP, n = 255 (28.4%); LOP, ∣n = 644 (71.6%)
Nonsignificant results Left numbers EOP, n = 466 Right numbers LOP, n = 1270 |
P value |
Significant results EOP vs LOP ODDS ratios [95% CI] Underlined: difference with cut-off 34 weeks |
P value | ||||
---|---|---|---|---|---|---|---|
Gestation (mean,SD) | 2.9 vs 2.75 | .18 | Mother’s age (y,SD) | 29.7 vs 28.6 | .002 | ||
Parity (mean, SD | 1.30 vs 1.17 | .14 | Chronic hypertension | 12.9% vs 9.3% | 1.44 [1.04-2.0] | .02 | |
Primiparity | 45.3% vs 49.3% | OR 0.85 | .14 | Gestational diabetes | 12.1% vs 15.9% | 0.73 [0.53-1.01] | .06 |
Adolescents (<18 y) | 2.6% vs 3.7% | OR 0.69 | .25 | Antecedent perinatal deaths | 13.9% vs 9.7% | 1.49 [1.0-2.2] | .05 |
Grand multiparae (5+) | 11.2% vs 9.5% | OR 1.2 | .29 | Antecedent preeclampsia | 14.5% vs 7.5% | 2.07 [1.4-3.0] | .0001 |
Single mother | 36.1% vs 37.7% | OR 0.93 | .53 | ||||
Years of schooling ≥10 | 55.3% vs 55.4% | OR 1.0 | .97 | ||||
BMI ≥25 kg/m2 | 55.2% vs 53.1% | OR 1.09 | .47 | ||||
BMI ≥30 kg/m2 | 28.6% vs 29.3% | OR 0.97 | .79 | ||||
Preexisting diabetes | 4.3% vs 4.4% | OR 0.99 | .96 | ||||
Smoking | 9.9% vs 8.6% | OR 1.12 | .40 | ||||
Antecedent miscarriage | 312% vs 30.7% | OR 1.03 | .85 | ||||
Antecedent abortion | 27.4% vs 23.1% | OR 1.26 | .12 | ||||
Antecedent thyroid diseasea | 1.5% vs 1.3% | OR 1.12 | .79 | ||||
Antecedent renal disease | 1.7% vs 0.9% | OR 1.99 | .20 | ||||
Medically induced | 2.1% vs 1.5% | OR 1.4 | .34 | ||||
Allergy/asthma | 7.1% vs 7.1% | OR 0.99 | .49 | ||||
Differences from cut-off at 34 weeks’ gestation | |||||||
Items becoming NON significant | Items becoming SIGNIFICANT | ||||||
Primigravidity | 32.0% vs 36.3% | OR 0.82 | .09 | Coagulopathyb | 1.3% vs 0.5% | OR 2.7 | .07 |
Pre-pregnancy/booking BMI | 26.7 vs 26.9 kg/M2 | .60 | 35 y+ | 27.5% vs 23.5% | OR 1.23 | .09 |
Thyroid diseases: goiter, hypo/hyperthyroidism, thyroidectomy, thyroid node, thyroiditis.
“Coagulopathies”: antiphospholipid syndrome, protein C/protein S deficit, factor 5, Leyden or other coagulation factors.