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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: J Allergy Clin Immunol. 2020 Mar 16;146(4):884–893.e5. doi: 10.1016/j.jaci.2020.02.032

Figure 3. Effect of omeprazole on calcium flux and signaling pathways downstream of FcεRI.

Figure 3.

A) Representative SYK and ERK phosphorylation blots and compiled ratios of phospho protein/total protein intensities in IgE-sensitized BMMCs treated or untreated (DMSO) with omeprazole for two hours. Statistics calculated following two-way ANOVA. B) Mobilization of calcium from intracellular stores following antigen stimulation of IgE-sensitized BMMCs treated with omeprazole for two hours or untreated (DMSO). P-value calculated by two-way ANOVA between DMSO and omeprazole (50 μM). Data are shown for one experiment representative of at least 2 independent experiments.