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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: J Allergy Clin Immunol. 2020 Mar 16;146(4):884–893.e5. doi: 10.1016/j.jaci.2020.02.032

Figure 4. Effect of omeprazole on passive systemic anaphylaxis.

Figure 4.

A) Change in core body temperature of mice treated with omeprazole or drug vehicle, sensitized with SPE-7, and challenged with DNP-BSA. Statistical analysis by two-way analysis of variance. B) Serum concentration of MCPT-1 in animals from PSA experiment at endpoint. C) Plasma histamine concentration in animals 5 minutes after allergen challenge. Statistical analysis by unpaired t-test. Data are from one experiment representative of 2 independent experiments with n = 4–5 for temperature drop and MCPT1 levels; histamine levels are from one experiment with n = 3–4 animals. **P<0.01 and ***P<0.001