A) Measurement of changes in pH by of intracellular vesicles by Lysosensor blue following treatment with omeprazole and bafilomycin. B) Loss of quenching of FITC-dextran in BMMCs treated with omeprazole or chloroquine. C) Measurement of changes in cytosolic pH by pHrodoGreen following treatment with omeprazole, chloroquine or bafilomycin. Statistical analysis by one-way analysis of variance. Data are shown from one representative of two experiments. MFI, mean fluorescence intensity. *P<0.05, **P<0.01, ***P<0.001 , and ****P<0.0001