Skip to main content
. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: J Allergy Clin Immunol. 2020 Mar 16;146(4):884–893.e5. doi: 10.1016/j.jaci.2020.02.032

Figure 6. Omeprazole inhibits differentiation of myeloid precursor cells to mast cells.

Figure 6.

A) Maturation of precursor cells to BMMCs in the presence or absence of omeprazole. Statistical analysis by two-way analysis of variance. B) Percentage of small intestinal mast cells among CD45+ cells in mice intraperitoneally injected with immune complexes of IL-4 and anti-IL-4 (IL4C) to induce mastocytosis and intragastrically treated with omeprazole. For in vitro mast cell differentiation, data is from one experiment involving three independent cultures; the in vivo experiment was repeated twice, and data are shown for one experiment. *P<0.05