Table 3.
Results of multiple linear regression examining the combined effects of HIV and METH on CSF norepinephrine
| Parameter | beta (SE) | 95% CI | p |
|---|---|---|---|
| HIVa | 0.75 (0.21) | 0.34, 1.16 | <0.001 |
| METHb | 0.45 (0.19) | 0.08, 0.81 | 0.017 |
| HIV x METH | −0.96 (0.26) | −1.47, –0.45 | <0.001 |
| Lifetime MDD | 0.28 (0.13) | 0.02, 0.54 | 0.035 |
| Antidepressant use | −0.34 (0.14) | −0.62, –0.06 | 0.017 |
| White (vs. not White) | 0.22 (0.13) | −0.04, 0.48 | 0.099 |
Represents effect of HIV+ vs. HIV- in METH- individuals only (reference group)
Represents effect of METH+ vs. METH- in HIV- individuals only (reference group)