The first column represents models using the methylation values BMIQ-normalized for Type I/II Probe Bias, and the second column represents models using the Illumina-normalized methylation values. The first row represents Manhattan plots, the second row are p value histograms, and the third row are QQ plots. In the Manhattan plot, the first dashed purple line represents the FDR cut off for significance, and the dashed green line represents the classic Bonferroni cut off for significance.