Table 4.

Multivariate Logistic Regression Analysis of Risk Factors for High-Grade Dysplasia or CRC in UC

Variable	Univariate			Multivariate
	OR (95% CI)	p-value		OR (95% CI)	p-value
Colorectal stricture	11.630 (4.261–31.747)	<0.001		9.350 (2.842–30.762)	<0.001
Inflammatory polyps	5.410 (2.058–14.222)	0.001		5.463 (1.692–17.638)	0.005
Age at diagnosis (≥40 yr)	4.590 (1.301–16.189)	0.018		8.499 (1.903–37.956)	0.005
Disease duration (≥10 yr)	4.300 (1.646–11.230)	0.003		3.223 (1.040–9.985)	0.043
PSC	5.893 (1.390–24.986)	0.016		1.441 (0.221–9.393)	0.703
Family history (CRC or IBD)	1.488 (0.646–3.422)	0.349		-	-
Steroids	0.396 (0.153–1.024)	0.056		-	-

CRC, colorectal cancer; UC, ulcerative colitis; OR, odds ratio; CI, confidence interval; PSC, primary sclerosing cholangitis; IBD, inflammatory bowel disease.