Table 2.
Review of the literature regarding PSP of the lung.
| Author/year | Patients enrolled (n) | Gender (M/F) | Age (Mean) | Type of treatment | IHC marker | Methastatic lymphonodes | Recurrence |
|---|---|---|---|---|---|---|---|
| Hu et al. (26) | 46 | 5 M 41 F | 51.4 | 45/46 Surgery −21 enucleation −9 wedge resections −15 lobectomies |
/ | / | No |
| Devouassoux- Shisheboran et al. (18) | 100 | 17 M 83 F | 46 | 54/100 Surgery: 5 wedge resections 37 lobectomies 2 bilobectomies 1 pneumonectomy - 9 procedures not specified specificata |
-pancytokeratin+; CAM 5.2+, CK7 +, EMA + calretinin –; CK5/6 – TTF1 +; Sp A e B + chromogranin –; synaptophysin –; Leu 7 – - S100 - |
Yes, 1 case | No |
| Shin et al. (27) | 76 | 9 M 67 F |
50 | 45/76 Surgery: 33 segmentectomies 11 lobectomies - 1 bilobectomies |
TTF1+, cytokeratin +, EMA+; - ki-67– |
/ | / |
| Yang et al. (28) | 59 | 2 M 57 F |
49.85 | Wedge resection (58 wedge resections) | Surface cell AE1/AE3+ e CK7+; Stromal cell AE1/AE3- e CK7+; - TTF1+ e EMA+ |
No | No |
| Lei et al. (29) | 28 | 3 M 25 F |
46.1 | 13 enucleation 7 wedge resection 8 lobectomies |
/ | No | Yes |
| Park et al. (30) | 32 | 1 M 31 F |
47.8 | 19 lobectomies 5 wedge resections 1 segmentectomy 7 wedge resections |
/ | Yes, 1 case | No |
| Cho et al. (31) | 11 | 1 M 10 F |
48.6 | Surgery | MMP-9 + Tubulinα + IGF1 + |
/ | / |
| Schmidt (32) | 6 | / | / | / | TTF1 + Napsin A + |
/ | / |
| Wu et al. (33) | 18 | 2 M 16 F |
44.6 | / | P40 + TTF1+, SHL+, EMA+, Vimentin+ |
No | No |
| Lovrenski et al. (34) | 6 | 1 M 5 F |
/ | Surgery | TTF1+ e panCK + | No | No |
This Table shows treatments and immunohistochemical characteristics. ALDH and SOX-2 have been never considered.