Table 4.
Characteristics | Univariate Analysis | Multivariate Analysis | |||||
---|---|---|---|---|---|---|---|
OR | 95% CI | P-value | OR | 95% CI | P-value | ||
Age (years) | <65 vs. ≥65 | 1.14 | 0.877–0.959 | 0.136 | 1.343 | 1.125–1.603 | 0.090 |
Gender | Male vs. Female | 1.042 | 0.868–1.252 | 0.658 | 0.988 | 0.817–1.195 | 0.900 |
Tumor location | Upper vs. Other | 0.973 | 0.810–1.168 | 0.769 | 0.868 | 0.722–1.044 | 0.134 |
T stage | T2 vs. T1 | 3.119 | 0.960–10.130 | 0.058 | |||
T3 vs. T1 | 3.953 | 1.253–12.470 | 0.019 | ||||
T4 vs. T1 | 6.455 | 2.073–20.100 | 0.001 | ||||
N stage | N1 vs. N0 | 1.999 | 1.379–2.897 | <0.001 | |||
N2 vs. N0 | 2.453 | 1.733–3.471 | <0.001 | ||||
N3 vs. N0 | 3.94 | 2.888–5.376 | <0.001 | ||||
TNM stage | II vs. I | 1.29 | 0.725–2.294 | 0.386 | 1.339 | 0.753–2.385 | 0.32 |
III vs. I | 2.864 | 1.668–4.889 | <0.001 | 3.018 | 1.763–5.164 | <0.001 | |
IV vs. I | 6.669 | 3.825–11.628 | <0.001 | 7.155 | 4.083–12.538 | <0.001 | |
CLDN18-ARHGAP26/6 fusion | Positive vs. Negative | 1.629 | 1.247–2.127 | <0.001 | 1.365 | 1.031–1.809 | 0.03 |
OR, odds ratio; 95% CI, 95% confidence interval.
Only TNM stage entered into the Cox regression model due to the potentially confounding effect.