Table 3:
Neurological disorders or complications associated with COVID-19 infection (N = 33)
| Neurological disorder/complications | Sources | Frequency, n (%*) | Neurological symptoms | Outcome (n) |
|---|---|---|---|---|
| Acute cerebral infarction | Li et al.14 | 11 (33.3) | NS | Recovered (7); dead (4) |
| Mao et al.3 | 4 (12.1) | NS | NR (4) | |
| Zhang et al.46 | 3 (9.1) | Headache | NR (3) | |
| Acute intracerebral hemorrhage | Li et al.14 | 1 (3.0) | NS | Recovered |
| Mao et al.3 | 1 (3.0) | NS | Dead | |
| Sharifi-Razavi et al.50 | 1 (3.0) | Acute loss of consciousness, Glasgow coma scale 7, and bilateral extensor plantar reflexes | NR | |
| Vu et al.51 | 1 (3.0) | Dysarthria, right hemiparesis, and right facial droop | NR | |
| Cerebral sinus venous thrombosis | Li et al.14 | 1 (3.0) | NS | Dead |
| Encephalopathy | Filatov et al.43 | 1 (3.0) | Headache, altered mental status, encephalopathic, nonverbal, and unable to follow any commands | NR |
| Yin et al.54 | 1 (3.0) | Insomnia, muscle soreness, lethargic and unresponsive, positive bilateral ankle clonus, lower left limb was positive for the Babinski sign and Chaddock sign, neck stiffness | Recovered | |
| Acute necrotizing hemorrhagic encephalopathy | Poyiadji et al.47 | 1 (3.0) | Altered mental status | NR |
| Encephalitis | Moriguchi et al.49 | 1 (3.0) | Headache, convulsion and impaired consciousness, and neck stiffness | NR |
| Ye et al.53 | 1 (3.0) | Confusion, nuchal rigidity, present extensor plantar response | Recovered | |
| Oculomotor nerve palsy | Wei et al.52 | 1 (3.0) | Diplopia and left eyelid drooping | Dead |
| Isolated sudden-onset anosmia | Gane et al.45 | 1 (3.0) | Impairment of smell | Recovered |
| Miller–Fisher syndrome | Gutiérrez-Ortiz et al.56 | 2 (6.1) | Anosmia and ageusia, right internuclear ophthalmoparesis, right fascicular oculomotor palsy, ataxia, and areflexia | Recovered (2) |
| Guillain–Barré syndrome | Zhao et al.55 | 1 (3.0) | Weakness of both legs, muscle strength 4/5 both arms and 3/5 both legs, areflexive, sensation to light touch and pinprick was decreased distally | Recovered |
NR = not reported; NS = not specified.
*
Percentages among patients with COVID-19 infection with neurological disorders/complications.