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. 2020 Sep 2;10:1508. doi: 10.3389/fonc.2020.01508

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Copyright © 2020 Zhen-Hua, Yi-Wei, Li-Qin, Jie-Yun, Zhe and Wei-Jian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Various levels of C1RL-AS1 expression in gastric cancer cell lines. (B) The silencing efficacy of siRNA and ASOs in HGC-27 and AGS cells was detected by qPCR. (C,D) Colony formation assays with representative images of HGC-27 and AGS cells after transfection with lncRNA C1RL-AS1 siRNA and ASO. (E,F) CCK-8 assays of HGC-27 and AGS cells after inhibiting C1RL-AS1 expression with siRNA and ASOs. Data are shown as the mean ± SEM, n = 3. *p < 0.05, **p < 0.01, ***p < 0.001.