Figure 3.

Superantigen Phl p 7 interactions with Fab. Cartoon representation of a complex between two Fab fragments of a human antibody and two molecules of timothy grass pollen allergen Phl p 7 (PDB code: 5OTJ). The crystal structure revealed an unusual binding of two molecules of the monomeric allergen and two molecules of the antibody. Phl p 7 molecules are shown in gray. Light chains of the antibody are shown in blue and heavy chains in purple. Calcium ions bound by the allergen are presented as red spheres.