Table 1.
Results of the Mendelian Randomization (MR) analysis for 10-heptadecenoate (17:1) and cardiovascular events.
| Exposures | MR | Heterogeneity | Pleiotropy | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Method | beta | SE | p | Method | Q | p | Intercept | SE | p | |
| Coronary heart disease | MR Egger | 0.8635 | 1.306 | 0.5447 | MR-Egger | 2.963 | 0.558 | −0.023 | 0.025 | 0.415 |
| WM | −0.2906 | 0.2939 | 0.3228 | |||||||
| IVW | −0.3047 | 0.23 | 0.1852 | IVW | 3.863 | 0.576 | ||||
| RAPS | −0.298 | 0.245 | 0.2239 | |||||||
| Myocardial infarction | MR Egger | 2.281 | 1.457 | 0.1925 | MR-Egger | 2.003 | 0.736 | −0.054 | 0.028 | 0.124 |
| WM | −0.2342 | 0.3345 | 0.4838 | |||||||
| IVW | −0.505 | 0.2754 | 0.06677 | IVW | 5.774 | 0.362 | ||||
| RAPS | −0.544 | 0.304 | 0.07355 | |||||||
| Cardioembolic stroke | MR Egger | −2.272 | 4.623 | 0.6488 | MR-Egger | 3.426 | 0.485 | 0.043 | 0.088 | 0.652 |
| WM | −0.4173 | 1.073 | 0.6973 | |||||||
| IVW | −0.05633 | 0.8168 | 0.945 | IVW | 3.725 | 0.596 | ||||
| RAPS | −0.1773 | 0.8609 | 0.8368 | |||||||
| Ischemic stroke | MR Egger | 1.04 | 2.317 | 0.6769 | MR-Egger | 1.266 | 0.865 | −0.022 | 0.044 | 0.638 |
| WM | −0.09585 | 0.5161 | 0.8527 | |||||||
| IVW | −0.121 | 0.4098 | 0.7679 | IVW | 1.595 | 0.911 | ||||
| RAPS | −0.1232 | 0.4288 | 0.7738 | |||||||
WM, Weighted median; IVW, Inverse variance weighted; SE, standard error; beta, beta-coefficients; MR, Mendelian randomization; RAPS, Robust Adjusted Profile Score.