Table 3.
Results of the Mendelian Randomization (MR) analysis for Oleic acid (18:1) and cardiovascular events.
| Exposures | MR | Heterogeneity | Pleiotropy | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Method | beta | SE | p | Method | Q | p | Intercept | SE | p | |
| Coronary heart disease | MR Egger | −2.516 | 2.943 | 0.4828 | MR-Egger | 3.695 | 0.156 | 0.034 | 0.043 | 0.514 |
| WM | −0.5437 | 0.5185 | 0.2944 | |||||||
| IVW | −0.2417 | 0.5068 | 0.6334 | IVW | 4.856 | 0.189 | ||||
| RAPS | −0.3834 | 0.4266 | 0.3687 | |||||||
| Myocardial infarction | MR Egger | −2.551 | 2.849 | 0.4651 | MR-Egger | 2.756 | 0.246 | 0.036 | 0.042 | 0.477 |
| WM | −0.3194 | 0.5727 | 0.5771 | |||||||
| IVW | −0.119 | 0.502 | 0.8125 | IVW | 3.856 | 0.286 | ||||
| RAPS | −0.2092 | 0.4717 | 0.6574 | |||||||
| Cardioembolic stroke | MR Egger | −10.12 | 7.623 | 0.3155 | MR-Egger | 0.418 | 0.812 | 0.16 | 0.11 | 0.274 |
| WM | 1.591 | 1.757 | 0.365 | |||||||
| IVW | 1.059 | 1.378 | 0.4419 | IVW | 2.693 | 0.469 | ||||
| RAPS | 1.088 | 1.464 | 0.4572 | |||||||
| Ischemic stroke | MR Egger | −1.607 | 3.805 | 0.7139 | MR-Egger | 0.736 | 0.695 | 0.024 | 0.055 | 0.708 |
| WM | 0.06184 | 0.7951 | 0.938 | |||||||
| IVW | 0.008491 | 0.6867 | 0.9901 | IVW | 0.923 | 0.823 | ||||
| RAPS | 0.008555 | 0.711 | 0.9904 | |||||||
WM, Weighted median; IVW, Inverse variance weighted; SE, standard error; beta, beta-coefficients; MR, Mendelian randomization; RAPS, Robust Adjusted Profile Score.