Table 4.
Results of the Mendelian Randomization (MR) analysis for Palmitoleic acid (16:1) and cardiovascular events.
| Exposures | MR | Heterogeneity | Pleiotropy | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Method | beta | SE | p | Method | Q | p | Intercept | SE | p | |
| Coronary heart disease | MR Egger | 0.6596 | 0.6251 | 0.402 | MR-Egger | 0.336 | 0.845 | −0.022 | 0.017 | 0.331 |
| WM | −0.1111 | 0.3084 | 0.7186 | |||||||
| IVW | −0.06957 | 0.2514 | 0.782 | IVW | 1.956 | 0.586 | ||||
| RAPS | −0.07158 | 0.2659 | 0.7878 | |||||||
| Myocardial infarction | MR Egger | 0.5029 | 0.7292 | 0.5617 | MR-Egger | 0.485 | 0.786 | −0.015 | 0.02 | 0.523 |
| WM | 0.07973 | 0.3459 | 0.8177 | |||||||
| IVW | −0.01255 | 0.2845 | 0.9648 | IVW | 1.078 | 0.782 | ||||
| RAPS | −0.01271 | 0.2963 | 0.9658 | |||||||
| Cardioembolic stroke | MR Egger | −5.925 | 4.205 | 0.2942 | MR-Egger | 1.163 | 0.559 | 0.17 | 0.098 | 0.230 |
| WM | 1.211 | 1.266 | 0.3385 | |||||||
| IVW | 1.042 | 1.16 | 0.3687 | IVW | 4.075 | 0.256 | ||||
| RAPS | 1.191 | 1.073 | 0.2667 | |||||||
| Ischemic stroke | MR Egger | −2.481 | 1.977 | 0.3362 | MR-Egger | 1.775 | 0.415 | 0.056 | 0.047 | 0.354 |
| WM | −0.3666 | 0.6421 | 0.5681 | |||||||
| IVW | −0.1862 | 0.5075 | 0.7137 | IVW | 3.265 | 0.326 | ||||
| RAPS | −0.1927 | 0.5236 | 0.7129 | |||||||
WM, Weighted median; IVW, Inverse variance weighted; SE, standard error; beta, beta-coefficients; MR, Mendelian randomization; RAPS, Robust Adjusted Profile Score.