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. 2020 Sep 2;10:1518. doi: 10.3389/fonc.2020.01518

Table 4.

Baseline characteristics of the sequence of radiation therapy with immunotherapy in PDAC patients with no surgery.

Variable RT and immx within 30 days Immx >30 days before RT RT >30 days before immx Total P
of each other n = 15 (6.64) n = 34 (15.04) n = 226
n = 177 (78.32)
Age at diagnosis (mean) 61.0 (33–85) 70.0 (47–80) 64.0 (80–37) 62.0 (33–85)
Sex Male 99 (55.93) 10 (66.67) 15 (44.12) 124 (54.87) 0.285
Female 78 (44.07 5 (33.33) 19 (55.88) 102 (45.13)
Race White 154 (89.53) 12 (80.00) 29 (85.29) 195 (88.24) 0.367
Black 12 (6.98) 2 (13.33) 5 (14.71) 19 (8.60)
Other 6 (3.49) 1 (6.67) 0 (0.00) 7 (3.17)
Unknown 5 0 0 5
Education ≥13% NHD 58 (32.95) 7 (46.67) 11 (32.35) 76 (33.78) 0.550
<13% 118 (67.05) 8 (53.33) 23 (67.65) 149 (66.22)
Unknown 1 0 0 1
Income ≥$35,000 123 (69.89) 8 (53.33) 24 (70.59) 155 (68.89) 0.402
<35,000 53 (30.11) 7 (46.67) 10 (29.41) 70 (31.11)
Unknown 1 0 0 1
Place of living Urban 168 (97.67) 15 (100.00) 33 (100.00) 216 (98.18) 0.566
Rural 4 (2.33) 0 (0.00) 0 (0.00) 4 (1.82)
Unknown 5 0 1 6
Hospital type Academic 137 (78.29) 5 (33.33) 25 (75.76) 167 (74.89) 0.0006
Community 38 (21.71) 10 (66.67) 8 (24.24) 56 (25.11)
Unknown 2 0 1 3
Insurance Yes 148 (98.67) 14 (100.00) 33 (97.06) 195 (98.48) 0.701
No 2 (1.33) 0 (0.00) 1 (2.94) 3 (1.52)
Unknown 27 1 0 28
Charlson score 0 149 (84.18) 7 (46.67) 25 (73.53) 181 (80.09) 0.001
1 23 (12.99) 5 (33.33) 8 (23.53) 36 (15.93)
≥2 5 (2.82) 3 (20.00) 1 (2.94) 9 (3.98)
Year of diagnosis 2004–2010 148 (83.62) 6 (40.00) 5 (14.71) 159 (70.35) 0.0001
2011–2016 29 (16.38) 9 (60.00) 29 (85.29) 67 (29.65)

RT, radiation therapy; Immx, immunotherapy; bf, before; NHD, no high school degree.