Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 2;10:1713. doi: 10.3389/fonc.2020.01713

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Dong, Cao, Luo, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

DSCR8 promoted tumor growth and epithelial–mesenchymal transition (EMT) in vivo. A2780 with overexpressed DSCR8 and SKOV-3 with knocked down DSCR8 were injected into nude mice. Four weeks later, tumor tissues from nude mice were isolated. (A) Tumor images of each group. (B) Tumor volume of each group. **P < 0.01, ***P < 0.001 vs. NC or sh-NC group, respectively. (C) Tumor weight of each group. (D,G). Western blot was used to measure the apoptosis (Bax, Bcl2, and Caspase3) in the formed tissues. (E,F,H,I). Immunohistochemistry and western blot were used to detect EMT-related proteins (E-cadherin, Vimentin, and N-cadherin) levels in tumor tissues. ***P < 0.001.