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. 2020 Sep 2;10:1713. doi: 10.3389/fonc.2020.01713

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Copyright © 2020 Dong, Cao, Luo, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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DSCR8 targeted miR-98-5p. (A) Through lncBase v.2 (http://carolina.imis.athena-innovation.gr/diana_tools/web/index.php?r=lncbasev2%2Findex), we predicted the targets of long non-coding RNA (lncRNA) DSCR8 and found that miR-98-5p is one of the targets of DSCR8. (B) RT-PCR was used to detect DSCR8 and miR-98-5p in the cytoplasm and nucleus. (C) RT-PCR was adopted for monitoring miR-98-5p, which selectively regulates DSCR8 in OC cells. (D,E) Dual luciferase reporter assay was performed to verify miR-98-5p and DSCR8 correlation. (F,G) The relationship between miR-98-5p and DSCR8 was verified by RNA immunoprecipitation (RIP) experiments. NS = P > 0.05, ***P < 0.001.