Table 5. Age-adjusted and multivariable hazard ratios (HRs) of mortality from respiratory diseases according to baseline history of diabetes, stratified by body mass index.
Body mass index <25 kg/m2 | Body mass index ≥25 kg/m2 | ||||||
Baseline history of diabetes | Baseline history of diabetes | Pinteraction | |||||
Yes | No | P trend | Yes | No | P trend | ||
Person-years | 33,391 | 1,006,460 | 11,541 | 273,969 | |||
Total respiratory diseases | |||||||
Deaths | 125 | 2,063 | 27 | 323 | |||
HRa (95% CI) | 1.39 (1.16–1.66) | 1.00 | <0.001 | 1.66 (1.12–2.46) | 1.00 | 0.01 | 0.78 |
HRb (95% CI) | 1.19 (0.99–1.43) | 1.00 | 0.06 | 1.63 (1.08–2.45) | 1.00 | 0.02 | 0.99 |
Respiratory infection | |||||||
Deaths | 92 | 1,255 | 19 | 203 | |||
HRa (95% CI) | 1.68 (1.36–2.08) | 1.00 | <0.001 | 1.90 (1.19–3.05) | 1.00 | 0.01 | 0.39 |
HRb (95% CI) | 1.48 (1.19–1.84) | 1.00 | <0.001 | 1.82 (1.12–2.98) | 1.00 | 0.02 | 0.54 |
COPD | |||||||
Deaths | 11 | 344 | 4 | 31 | |||
HRa (95% CI) | 0.72 (0.40–1.32) | 0.29 | 0.29 | 2.15 (0.76–6.12) | 1.00 | 0.15 | 0.98 |
HRb (95% CI) | 0.56 (0.31–1.03) | 1.00 | 0.06 | 2.13 (0.72–6.31) | 1.00 | 0.17 | 0.88 |
Other respiratory diseases | |||||||
Deaths | 22 | 464 | 4 | 89 | |||
HRa (95% CI) | 1.09 (0.71–1.68) | 1.00 | 0.68 | 0.91 (0.33–2.49) | 1.00 | 0.86 | 0.44 |
HRb (95% CI) | 0.95 (0.62–1.47) | 1.00 | 0.82 | 0.93 (0.33–2.57) | 1.00 | 0.88 | 0.41 |
CI, confidence interval; COPD, chronic obstructive pulmonary disease; HR, hazard ratio.
aAdjusted for age.
bAdjusted for age, sex, educational level, smoking, alcohol consumption, sports activity, walking time, family history of diabetes.