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. 2020 Aug 7;7:14. doi: 10.21037/sci-2020-015

Table 1. Marginal means of ARS and ALP values of different groups and their effect over time (two-way ANOVA).

−VE CT +VE CT S1 (PCL/Alg) S2 (PCL/Alg/Ca) S3 (PCL/Alg/Ca/n-HA) P
ARS 0.0643±0.0163 0.1133±0.0210a 0.1027±0.0187a 0.1027±0.0183a 0.1507±0.0253a,b,c,d <0.001
ALP 1.031±0.171 0.563±0.094a 0.772±0.129a,b 1.063±0.177b,c 1.068±0.178b,c <0.001

a, significance vs. −ve control group; b, significance vs. +ve control group; c, significance vs. S1 group; d, significance vs. S2 group within each time period. P, probability P<0.05. ANOVA, analysis of variance; ARS, Alizarin red S; ALP, alkaline phosphatase; PCL/Alg, polycaprolactone/alginate; n-HA, nano-hydroxyapatite.