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. 2020 Aug 12;13:249–264. doi: 10.2147/JAA.S261271

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© 2020 Plesa et al.

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mRNA expression of TGF-β1 or TNF-α-IL-1β-induced fibrogenic markers/CCL-chemokines in NHBFCs or DHBFCs in response to 1,25(OH)₂D₃ (50 nM) treatment: FN 1 (A), LUM (B), BGN (C), COL5A1 (D), MMP2 (E), TIMP1 (F), CCL2 (G), CCL5 (H) and CCL11 (I). The Student’s t-test (variances assumed equally by ANOVA) was used to determine the difference between NHBFCs and DHBFCs under a given treatment and associated p- values are indicated. (ns) p > 0.05, no significant difference in mean fold change mRNA expression. Data were expressed as mean ± standard error (SE) from duplicate values of two independent experiments. NHBFCs (n=4), DHBFCs (n=4).