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. 2020 Sep 2;14:266. doi: 10.3389/fncel.2020.00266

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Copyright © 2020 Koroleva, Ermakova, Mustafina, Giniatullina, Giniatullin and Sitdikova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of the H₂S donor NaHS on ATP-induced mast cell degranulation. Images (×20) of Toluidin Blue stained rat meninges after incubation in basic solution (A) and after exposure to ATP (100 μM, B), BzATP (30 μM, C), NaHS (100 μM, D) or combination of NaHS+ATP (E) and NaHS+BzATP (F). Notice red arrows indicating degranulated mast cells. Inserts (a) and (b) shows enlarged intact and degranulated mast cells (×63). (G) Histograms showing the percent of degranulated mast cells under various conditions (n = 6). *p < 0.05.