Lipidomic profiles and depressive symptoms (DS). (A)
Orthogonal projections to latent structures discriminant
analysis (OPLS-DA) score plot showed clear separation
between women with Center for Epidemiologic Studies
Depression Scale (CES-D) scores ≥23, which have been
correlated with DS, and the women with CES-D scores ≤22.
Blue = CES-D ≥ 23, green = CES-D ≤22. (B) DS model
predicted variable importance in projection (VIP) scatter
plot showing lipids with high VIP scores. (C) S-plot of
lipids identified to be related to DS. Blue triangles
indicate lipid species higher with CES-D score ≥23 and red
squares indicate lipid species lower with CES-D ≥ 23. (D)
PC(37:1) levels in preterm birth (PTB) and DS models.
Values represent mean, and error bars shows standard error
of the mean (*p value < .05, Student’s
t test).