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. Author manuscript; available in PMC: 2021 Nov 1.

Published in final edited form as: J Comp Neurol. 2020 May 5;528(16):2748–2766. doi: 10.1002/cne.24929

Fig. 5. — Differential expression of cholinergic enzymes (BCHE and CHAT) and nicotinic acetylcholine receptors (CHRNA2 and CHRNA4) in PreC CatD-positive layer III neurons in AD compared to NCI and MCI. Upregulation trend of BCHE (AD>NCI, p=0.2^t; AD>MCI, p=0.02^t) and CHRNA2 (AD>NCI, p=0.03^t; AD>MCI, p=0.02^t) in AD compared to NCI and MCI. Upregulation trend of CHAT (AD>NCI, p=0.04^t) and CHRNA4 (AD>NCI, p=0.02^t) in AD compared to NCI and significant upregulation of CHAT(AD>MCI, p=0.005) and CHRNA4 (AD>MCI, p=0.003) in AD compared to MCI. Key: ^t-trend: 0.01<p<0.05; *: p⩽0.01.