Table 6.
Quantitative PCR validation of select mRNA expression of PreC transcripts
|
Gene |
NCI (Mean±SD) (N=9) | MCI (Mean±SD) (N=9) | AD (Mean±SD) (N=8) |
p |
Multiple comparison |
|---|---|---|---|---|---|
| GALR1 | 0.26±0.137 | 0.40±0.334 | 0.22±0.065 | 0.644 | unchanged |
| BAP1 | 0.636±0.101 | 0.823±0.334 | 0.709±0.192 | 0.427 | unchanged |
| RBM3 | 0.207±0.154 | 0.169±0.155 | 0.324±0.233 | 0.202 | unchanged |
| RAB11A | 0.308±0.103 | 0.380±0.046 | 0.423±0.047 | 0.016 | AD>NCI |
| HOMER1 | 0.092±0.060 | 0.138±0.060 | 0.181±0.085 | 0.045 | AD>NCI |
| GNG2 | 0.247±0.208 | 0.196±0.0.178 | 0.242±0.069 | 0.623 | unchanged |
| GRM1 | 0.249±0.226 | 0.212±0.158 | 0.314±0.141 | 0.514 | unchanged |
| SLC2A5 | 0.996±1.237 | 0.813±0.440 | 1.240±1.537 | 0.572 | unchanged |
| TIMP1 | 1.823±1.874 | 2.531±2.125 | 1.586±1.358 | 0.451 | unchanged |
| RPS6KB1 | 0.168±0.066 | 0.240±0.098 | 0.215±0.062 | 0.159 | unchanged |
| CHAT | 0 | 0 | 0 |