Fig. 3.

Inherent toxicity of L-DOPA toxicity in wild type (WT) flies with longer exposure (92 hours), but not with shorter exposure (48 hours). (A) Wild type (WT) larvae treated with 5 or 10 mM L-DOPA showed a significant increase in body bending behavior (BBB) over WT Control when L-DOPA was treated from the first instar (for 92 hours). (B) WT larvae showed no changes in BBB when a high concentration (10 mM) of L-DOPA was exposed only during the third instar stage (48 hours). Student t-test, ***p<0.001. For each group, 18 larvae from 3 separate experiments were examined.