Fig. 4.

Rescue of locomotion defects in A53T larvae with 48 hour exposure to 100 µM L-DOPA. When treated with 100 µM of L-DOPA for 48 hours, locomotion deficits in speed (A), angular velocity (B) and pause time (C) were significantly rescued. Locomotion deficits were not completely rescued by L-DOPA as there is still a significant difference between A53T+100 µM L-DOPA and WT Control. Student t-test, *p<0.05; **p<0.01; ***p<0.001. For each group, 9~18 larvae from 3 separate experiments were examined.