. 2020 Sep 14;6(9):e04894. doi: 10.1016/j.heliyon.2020.e04894

Table 8.

Analgesic and anti-inflammatory activity of gels.

Mediators	% Inhibition F1 (0:100)	F2 (25:75)	F3 (50:50)	F4 (75:25)	F5 (100:0)	Diclofenac Gel
COX-2	38.58 ± 3.84^b	34.86 ± 2.72^b	49.70 ± 2.14^b	54.36 ± 3.96^b	37.49 ± 1.76^b	61.67 ± 4.72^a
IL-10	6.60 ± 0.56^b	9.72 ± 0.83^b	15.70 ± 0.55^b	9.22 ± 0.47^b	8.88 ± 1.41^b	21.25 ± 2.12^a
TNFα	33.32 ± 3.71^b	47.62 ± 2.16^b	51.05 ± 3.18^b	40.43 ± 3.54^b	26.66 ± 1.03^a	25.89 ± 1.36^a
PGE	10.94 ± 1.60^b	11.70 ± 1.05^b	19.79 ± 0.73^b	14.15 ± 3.36^b	7.65 ± 0.51^b	26.28 ± 1.36^a

Formulation ratios in the order of Chasmanthera dependens:Chenopodium ambrosioides. Data presented as Mean ± SEM (n = 3). Values carrying superscripts different from the control gel for each parameter are significantly different (p < 0.05).