Table 2.

Intra- and intergroup changes of outcome variables pre- and posttreatment.

Variables	Study group (n = 20)	Control group (n = 20)	p value
FVC (% pred.)
Pre-	78.5 ± 9.8	78.9 ± 10.5	0.891
Post-	93.2 ± 7.4	85.8 ± 11.3	0.019
p value	<0.001	0.053
FEV1 (% pred.)
Pre-	72.3 ± 8.5	72.7 ± 9.2	0.887
Post-	82.6 ± 7.2	77.4 ± 8.8	0.047
p value	0.002	0.107
VO2max (mL/kg/min)
Pre-	40.3 ± 7.4	40.7 ± 8.1	0.871
Post-	49.1 ± 7.9	43.5 ± 8.4	0.036
p value	0.008	0.290
VE/VCO2 slope
Pre-	31.6 ± 7.1	30.9 ± 6.8	0.752
Post-	24.5 ± 5.8	28.7 ± 6.2	0.033
p value	0.002	0.291
6-MWT
Pre-	421.3 ± 38.7	438.4 ± 44.5	0.203
Post-	488.5 ± 42.8	454.6 ± 51.2	0.028
p value	<0.001	0.292
PedsQL (overall score)
Pre-	75.41 ± 12.5	72.84 ± 11.9	0.509
Post-	82.73 ± 11.2	73.52 ± 11.7	0.015
p value	<0.001	0.632

FVC: forced vital capacity; FEV1: forced expiratory volume in one second; VO₂max: maximal oxygen uptake; VE/VCO₂: minute ventilation/carbon dioxide production; 6-MWT: six-minute walk test; PedsQL: pediatric quality of life inventory.