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. 2020 Sep 7;2020:4121750. doi: 10.1155/2020/4121750

Figure 3.

Figure 3

Overexpression of USP2 suppressed cardiac hypertrophy induced by pressure overload. (a) Histological analysis of heart sections from AAV9-Control or AAV9-USP2-treated mice following sham or TAC. (b and c) Heart weight to tibia length ratios (HW/TL) and body weight ratios (HW/BW) from AAV9-Control or AAV9-USP2-treated mice following sham or TAC. (d) Heart cross-sections were stained with wheat germ agglutinin (WGA). (e) Brain natriuretic peptide (BNP) mRNA levels in the hearts of AAV9-Control or AAV9-USP2-treated mice following sham or TAC. All values are presented as the relative value of the sham (AAV9-Control) value. ∗P < 0.05 and ∗∗P < 0.01 (AAV9-Control plus TAC vs. AAV9-Control plus sham); #P < 0.05 and ##P < 0.01 (AAV9-Control plus TAC vs. AAV9-USP2 plus TAC). n = 6/group.