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. 2020 Sep 5;2020:3280530. doi: 10.1155/2020/3280530

Figure 2.

Figure 2

miR-587 suppressed HCC cell proliferation. (a) The transfection efficiency of miR-587 mimic (p = 0.001) and inhibitor (p = 0.037). The MTT assay showed that miR-587 upregulation (b) suppressed the cell viability of SMMC-7721 cells, whereas miR-587 downregulation (c) fostered the cell viability (both p < 0.05). Flow cytometry analysis showed that the number of SMMC-7721 cells at G1 phase increased and those at S phase decreased in the miR-587 mimic group (d) (p = 0.001, p = 0.044, respectively). The number of SMMC-7721 cells at G1 phase decreased and those at S phase increased in the miR-587 inhibitor group (e) (p = 0.028, p = 0.048, respectively). ∗p < 0.05, ∗∗p < 0.01. miR: microRNA.