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. 2020 Sep 4;2020:9627974. doi: 10.1155/2020/9627974

Figure 1.

Figure 1

Overexpression of miR-29a-3p distinctly reduces aorta plaque formation for atherosclerosis (AS) mice. (a) Serum miR-29a-3p levels were examined in AS mice with or without miR-29a-3p mimic injection using RT-qPCR. (b, c) RT-qPCR was presented to detect miR-29a-3p as well as TNFRSF1A expression in AS mice with or without miR-29a-3p mimic injection. (d, e) TNFRSF1A protein expression was tested in AS mice with or without miR-29a-3p overexpression via western blot. (f–i) Biochemical test was performed to test the serum levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) in AS mice with or without miR-29a-3p mimic injection. (j) Representative images of H&E staining for aorta of AS mice. (k) Representative images of Masson's staining results for aorta of AS mice. ∗p < 0.05; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001.