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Upregulated miR-29a-3p inhibits migration as well as invasion of ox-LDL-induced vascular smooth muscle cells (VSMCs) via directly targeting TNFRSF1A in AS. (a–d) Transwell assays were carried out to examine the number of migrated and invaded ox-LDL-induced VSMCs in ox-LDL-induced VSMCs transfected with miR-29a-3p mimic and/or pcDNA3.1-TNFRSF1A. (e, f) MMP9 and MMP2 protein expression in ox-LDL-induced VSMCs. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗∗p < 0.0001.
