Figure 5.

Univariate analyses of more infusion (TIL numbers and CD8⁺ TIL percentage), less infusion (CD8⁺PD1⁺ TIL percentage and CD4⁺FoxP3⁺ TIL percentage), and HPV status and having fever or not after immunotherapy based on OS. OS curve for: (a) patients with more TIL numbers (≥50 × 10⁹, red line) and less TIL numbers (<50 × 10⁹, blue line); (b) patients with more CD8⁺ TIL (≥60%, red line) and less CD8⁺ TIL (<60%, blue line); (c) patients with more CD8⁺PD1⁺ TIL (≥10%, red line) and less CD8⁺PD1⁺ TIL (<10%, blue line); (d) patients with more CD4⁺FoxP3⁺ TIL (≥20%, red line) and less CD4⁺FoxP3⁺ TIL (<20%, blue line); (e) patients with HPV⁺ (red line) and HPV⁻ (blue line); and (f) patients having fever (red line) and no fever (blue line) after immunotherapy.