Table 3.
Characteristics of patients with ORR (N = 20) and non-ORR (N = 60).
| Characteristic | No. of ORR | No. of non-ORR | P value |
|---|---|---|---|
| Age (years) | |||
| ≥45 | 11 | 34 | |
| <45 | 9 | 26 | 0.896 |
| Pathological type | |||
| Squamous cell | 16 | 49 | |
| Adenocarcinoma | 4 | 11 | 0.869 |
| ECOG PS | |||
| 0 | 13 | 37 | |
| 1 | 7 | 23 | 0.790 |
| Size of primary tumor (cm) | |||
| ≥5 | 9 | 38 | |
| <5 | 11 | 22 | 0.149 |
| First-line chemotherapy with bevacizumab | |||
| Yes | 8 | 12 | |
| No | 12 | 48 | 0.074 |
| Location of metastatic tumors | |||
| Lung | 11 | 45 | |
| Others | 9 | 15 | 0.091 |
| Infusion of TIL numbers | |||
| ≥50 × 109 | 17 | 10 | |
| <50 × 109 | 3 | 50 | 0.000 |
| Infusion of CD8+ TIL percentage | |||
| ≥60% | 18 | 11 | |
| <60% | 2 | 49 | 0.000 |
| Infusion of CD8+PD1+ TIL percentage | |||
| ≥10% | 3 | 35 | |
| <10% | 17 | 25 | 0.001 |
| Infusion of CD4+FoxP3+ TIL percentage | |||
| ≥20% | 4 | 33 | |
| <20% | 16 | 27 | 0.007 |
| HPV status | |||
| Positive | 20 | 48 | |
| Negative | 0 | 12 | 0.030 |
| Fever | |||
| Yes | 20 | 34 | |
| No | 0 | 26 | 0.000 |