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. 2020 Sep 7;2020:9803024. doi: 10.1155/2020/9803024

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Copyright © 2020 Lu Ye et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Bmal1 deficiency in β-cells altered core genes related to mitochondrial dynamics. Bmal1, mitofusin 1, mitofusin 2, and fission 1 mRNA were analyzed by qPCR. Expression levels were normalized to GAPDH mRNA, and each bar represents the mean ± SE of 3 individual experiments. NC: normal control group; siRNA-NC: INS-1 cells treated with negative control siRNA; siRNA-Bmal1: INS-1 cells treated with Bmal1 siRNA. A p value < 0.05 is considered as statistically significant. ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001.